Chemical Composition of the Essential Oil of Litsea resinosa Blume and Acetylcholinesterase Activity

Authors

  • Abubakar Siddiq Salihu Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia
  • Nurunajah Ab Ghani Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor, Malaysia
  • Nurulfazlina Edayah Rasol Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor, Malaysia
  • Shamsul Khamis Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, Malaysia

DOI:

https://doi.org/10.37134/jsml.vol11.1.9.2023

Keywords:

Litsea resinosa, Lauraceae, essential oil, caryophyllene, acetylcholinesterase

Abstract

The essential oil of Litsea resinosa Blume (Lauraceae) was obtained by hydrodistillation and was fully characterized by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). A total of twenty-eight components were identified in the essential oil, which made up 90.8% of the total oil. The essential oil consists mainly of β-caryophyllene (22.5%), α-humulene (15.4%), caryophyllene oxide (9.2%), germacrene D (5.6%), and β-selinene (5.0%). The essential oil showed significant activity against acetylcholinesterase with a percentage inhibition of 72.4%.

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Author Biographies

Abubakar Siddiq Salihu, Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, 35900 Tanjong Malim, Perak, Malaysia

Department of Pure and Industrial Chemistry, Faculty of Natural and Applied Sciences, Umaru Musa Yar’adua University, Katsina, Nigeria

Nurunajah Ab Ghani, Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor, Malaysia

Faculty of Applied Sciences, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia

Nurulfazlina Edayah Rasol, Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA, 42300 Bandar Puncak Alam, Selangor, Malaysia

Faculty of Applied Sciences, Universiti Teknologi MARA, 40450 Shah Alam, Selangor, Malaysia

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Published

2023-03-21

How to Cite

Salihu, A. S., Ab Ghani, N., Rasol, N. E., & Khamis, S. (2023). Chemical Composition of the Essential Oil of Litsea resinosa Blume and Acetylcholinesterase Activity. Journal of Science and Mathematics Letters, 11(1), 64–67. https://doi.org/10.37134/jsml.vol11.1.9.2023

Issue

Vol. 11 No. 1 (2023): January

Section

Articles

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Copyright (c) 2023 Abubakar Siddiq Salihu, Nurunajah Ab Ghani, Nurulfazlina Edayah Rasol, Shamsul Khamis

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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