Phytochemicals and Antioxidant Activity of Anacardium occidentale L.

Authors

  • Maisarah Azad Khayruzamri Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 Johor Bahru, Johor, Malaysia
  • Wan Nur Aqilah Wan Mohd Samsudin Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 Johor Bahru, Johor, Malaysia
  • Siti Ernieyanti Hashim Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, 81310 Johor Bahru, Johor, Malaysia

DOI:

https://doi.org/10.37134/jsml.vol11.1.8.2023

Keywords:

Anacardium occidentale, isolation, spectroscopy, antioxidant

Abstract

Anacardium occidentale, locally known as “pokok gajus” is known for its medicinal purposes. The objectives of this study are to isolate compounds from the stem bark extract of A. occidentale and to study the antioxidant properties of the extracts. Cold maceration method was performed for the extraction of A. occidentale stem bark. Purification of the crude extracts using column chromatography successfully isolated two compounds. The isolated compounds were elucidated using spectroscopic methods including Fourier Transform Infrared and Nuclear Magnetic Resonance spectroscopy. These compounds were identified as stearic acid and β-sitosterol. The antioxidant potential of the crude extracts was determined using a 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay. The results revealed that methanol extract was most effective in the capability to scavenge free radicals as it exhibited the highest radical scavenging activity towards DPPH with an IC50 value of 87.67 µg/mL. Total phenolic content and total flavonoid content of the extracts were measured. Both total phenolic and flavonoid contents showed a good correlation with the antioxidant activity indicated that both compounds were the major contributors to the antioxidant capacity of the extracts. Based on the findings, A. occidentale can be considered as an effective source of natural antioxidants.

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References

Ajileye OO, Obuotor EM, Akinkunmi EO, Aderogba MA. (2015). Isolation and characterization of antioxidant and antimicrobial compounds from Anacardium occidentale L. (Anacardiaceae) leaf extract. Journal of King Saud University-Science, 27(3), 244-225.

Boy H, Rutilla A, Santos K, Ty A, Yu A, Mahboob T. (2018). Recommended medicinal plants as source of natural products: A review. Digital Chinese Medicine, 1(2), 131-142.

de Sousa Leite A, Islam MT, Júnior ALG, de Castro e Sousa JM, de Alencar MVOB, Jardim Paz MFC, Rolim HML, de Medeiros MGF, de Carvalho Melo-Cavalcante AA, Lopes JAD. (2016). Pharmacological properties of cashew (Anacardium occidentale). African Journal of Biotechnology, 15(35), 1855-1863.

Johari M, Khong H. (2019). Total phenolic content and antioxidant and antibacterial activities of Pereskia bleo. Advances in Pharmacological Sciences, 7428593, 1-4.

Madjitoloum B, Talla E, Nyemb J, Ngassoum M, Tsatsop T, Mahmout Y. (2018). Comparative survey of three processes used for the extraction of total phenol content and total flavonoid content of Anacardium occidentale L. and the assessment of its antioxidant activity. African Journal of Biotechnology, 17(40), 1265-1273.

Olatunji O. (2015). Isolation and characterization of the chemical constituents of Anacardium occidentale cracked bark. Natural Products Chemistry & Research, 3(5), 1-5.

Runjala S, Kella L. (2017). Cashew apple (Anacardium occidentale L.) therapeutic benefits, processing and product development: An overview. The Pharma Innovation Journal, 6(7), 260-264.

Uni W, Malaka M, Yanti N, Hartati R., Sukrasno, Sahidin I. (2018). Radical scavenging and antibacterial activity of phenolic compounds from Anacardium occidentale L. stem barks from South East Sulawesi-Indonesia. Indian Journal of Pharmaceutical Sciences, 80(1), 143-149.

Yuliana M, Nguyen-Thi B, Faika S, Huynh L, Soetaredjo F, Ju Y. (2014). Separation and purification of cardol, cardanol and anacardic acid from cashew (Anacardium occidentale L.) nut-shell liquid using a simple two-step column chromatography. Journal of the Taiwan Institute of Chemical Engineers, 45(5), 2187-2193.

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Published

2023-03-20

How to Cite

Khayruzamri, M. A., Wan Mohd Samsudin, W. N. A., & Hashim, S. E. (2023). Phytochemicals and Antioxidant Activity of Anacardium occidentale L. Journal of Science and Mathematics Letters, 11(1), 59–63. https://doi.org/10.37134/jsml.vol11.1.8.2023

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